Tubulopatías primarias

Nutrición y crecimiento

• Crecimiento, nutrición y metabolismo mineral en enfermedad renal crónica
• Nutrición neonatal
• Nutrición y afectación cardiovascular

Enfermo pediátrico crítico

• Biomarcadores y escalas de pronóstico
• Optimización de la ventilación mecánica

• Claramunt D, Gil-Peña H, Fuente R, García-López E, Hernández Frías O, Ordoñez FA,Rodríguez-Suárez J, Santos F. Effects of growth hormone treatment on growth plate, bone,and mineral metabolism of young rats with uremia induced by adenine. Pediatr Res. 2017;82:148-154.
• Sánchez-Illana Á, Núñez-Ramiro A, Cernada M, Parra-Llorca A, Valverde E, Blanco D, Moral-Pumarega MT, Cabañas F, Boix H, Pavon A, Chaffanel M, Benavente-Fernández I, Tofe I, Loureiro B, Fernández-Lorenzo JR, Fernández-Colomer B, García-Robles A, Kuligowski J, Vento M; HYPOTOP Study Group. Evolution of Energy Related Metabolites in Plasma from Newborns with Hypoxic-Ischemic Encephalopathy during Hypothermia Treatment. Sci Rep. 2017 Dec 6;7(1):17039.
• A. Sariego, C. Rey, A. Medina, J. Mayordomo, A. Concha, B. Prieto, A. Vivanco. C-reactive protein, procalcitonin and interleukin-6 in kinetics in pediatric postoperative patients. J Crit Care.2017 Oct; 41:119-123.
• González R, Bustiza A, Fernández SN, García M, Rodríguez S, García-Teresa MA, Gaboli M, García S, Sardón O, García D, Salcedo A, Rodríguez A, Luna MC, Hernández A, González C, Medina A, Pérez E, Callejón A, Toledo JD, Herranz M, López-Herce J. Quality of life in homeventilated children and their families. Eur J Pediatr. 2017 Oct;176(10):1307-1317.
• Gil-Peña H, Gómez J, Santos F, Coto E, Arango A, Hernandez O, Rodríguez J, Nadal I, Cantos V, Chocrón S, Vergara I, Madrid Á, Vazquez C, González LE, Blanco F. Primary distal renal tubular acidosis: novel findings in patients studied by next-generation sequencing. Pediatr Res. 2016; 7: 496-501.
• Santos F, Ordóñez FA, Claramunt-Taberner D, Gil-Peña H. Clinical and laboratory approaches in the diagnosis of renal tubular acidosis. Pediatr Nephrol. 2015; 30:2099-107.
• Ariceta G, Lara E, Camacho JA, Oppenheimer F, Vara J, Santos F, Muñoz MA, Cantarell C, Gil Calvo M, Romero R, Valenciano B, García-Nieto V, Sanahuja MJ, Crespo J, Justa ML, Urisarri A, Bedoya R, Bueno A, Daza A, Bravo J, Llamas F, Jiménez Del Cerro LA. Cysteamine (Cystagon®) adherence in patients with cystinosis in Spain: successful in children and a challenge in adolescents and adults. Nephrol Dial Transpl. 2015; 30:475-80.
• Tavira B, Gómez J, Santos F, Gil H, Alvarez V, Coto E. A labor- and cost-effective non-optical semiconductor (Ion Torrent) next-generation sequencing of the SLC12A3 and CLCNKA/B genes in Gitelman's syndrome patients. J Hum Genet. 2014; 59:376-80.
• Gil-Peña H, Mejía N, Santos F. Renal tubular acidosis. J Pediatr. 2014; 164:691-698.e1. Santos F, Fuente R, Mejia N, Mantecon L, Gil-Peña H, Ordoñez FA. Hypophosphatemia and growth. Pediatr Nephrol. 2013; 28:595-603.
• Riobello C, Gómez J, Gil-Peña H, Tranche S, Regu ero JR, de la Hera JM, Delgado E, Calvo D, Morís C, Santos F, Coto-Segura P, Iglesias S, Alonso B, Alvarez V, Coto E. KCNQ1 gene variants in the risk for type 2 diabetes and impaired renal function in the Spanish Renastur cohort. Mol Cell Endocrinol. 2016; 427:86-91.
• Claramunt D, Gil-Peña H, Fuente R, García-López E, Loredo V, Hernández-Frías O, Ordoñez FA, Rodríguez-Suárez J, Santos F. Chronic kidney disease induced by adenine: a suitable model of growth retardation in uremia. Am J Physiol Renal Physiol. 2015; 309:F57-62.
• Álvarez-García Ó, García-López E, Loredo V, Gil-Peña H, Mejía-Gaviria N, Rodríguez-Suárez J, Ordóñez FÁ, Santos F. Growth hormone improves growth retardation induced by rapamycin without blocking its antiproliferative and antiangiogenic effects on rat growth plate. PLoS One. 2012; 7:e34788.
• Ang L, Arboleda S, Licua G, Chuihui Y, Nan Q, Suarez M, Solís G, De Los Reyes-Gavilán GD, Gueimonde M. The establishment of the infant intestinal microbiome is not affected by rotavirus vaccination. Sci Rep. 2014; 4:7417.
• González-Iglesias H, de la Flor St Remy RR, López-Sastre J, Fernández-Colomer B, Ibáñez-Fernández A, Solís G, Sanz-Medel A, Fernández-Sánchez ML. Efficiency of iodine supplementation, as potassium iodide, during lactation: A study in neonates and their mother. Food Chem 2012; 133:859-865
• López-Vázquez A, Mozo L, Alonso-Arias R, Suárez-Álvarez B, Vidal-Castiñeira JR, Arranz E, Volta U, Bousoño C, López-Hoyos M, Rodrigo L, López-Larrea C. Autoantibodies against MHC class I polypeptide-related sequence A are associated with increased risk of concomitant autoimmune diseases in celiac patients. BMC Med. 2014. 25;12:34.
• López-Herce J, Del Castillo J, Cañadas S, Rodríguez-Núñez A, Rey C, Carrillo A, Spanish Study Group of Cardiopulmonary Arrest in Children. In-hospital pediatric cardiac arrest in Spain. Rev Esp Cardiol. 2014; 67: 189-195.
• Rey C, García-Hernández I, Concha A, Martínez-Camblor P, Botrán M, Medina A, Prieto B, López-Herce J. Pro-adrenomedullin, pro-endothelin-1, procalcitonin, C-reactive protein and mortality risk in critically ill children: a prospective study. Crit Care. 2013. 17;R240.
• López-Herce J, Ferrero L, Mencía S, Antón M, Rodríguez-Núñez A, Rey C, Rodríguez L.Teaching and training acute renal replacement therapy in children. Nephrol Dial Transpl. 2012; 27:1807-1811.
• Lobete C, Medina A, Rey C, Mayordomo-Colunga J, Concha A, Menéndez S. Correlation of oxygen saturation as measured by pulse oximetry/fraction of inspired oxygen ratio with PaO2/fraction of inspired oxygen ratio in a heterogeneous sample of critically ill children. J Critical Care. 2013; 28: 538.e1–538.e7.
• Mayordomo J, Pons M, López Y, Solana MJ, Rey C, Martinez P, Rodriguez A, López-Herce J, Medina A, Abadesso C, Gaboli M, García M, González M, Madurga P, González A, Oñate E. Predicting noninvasive ventilation failure in pediatric patients from the SPO2/FiO2 (SF) ratio. Intens Care Med. 2013; 39:1095-1103.
• De Luca D, Piastra M, Chidini G, Tissieres P, Calderini E. Essouri S, Medina Villanueva A, Vivanco Allende A, Pons Odena M, Perez Baena L, Hermon M, Tridente A, Conti G, Antonelli M, Kneyber M. Respiratory Section of the European Society for Pediatric Neonatal Intensive Care (ESPNIC). The use of Berlin definition for acute respiratory distress síndrome during infancy and early childhood: multicenter evaluation and expert consensus. Intens Care Med. 2013; 39:2083-91.

Estudio multicéntrico aleatorizado, doble ciego, comparando el uso de la hipotermia corporal total moderada precoz con topiramato o placebo en recién nacidos asfixiados evolucionando a encefalopatía hipóxico-isquémica moderada-severa

• Código: Estudio HYPOTOP.
• Nº EudraCT: 2011-005696-17.
• Promotor: Instituto de Investigación La Fe.
• Duración: 2012-2017

A Multicenter, Randomized, Placebo-Controlled Study of SBC-102 in Patients with Lysosomal Acid Lipase Deficiency

• Código: Estudio Synageva LAL-CL02
• Promotor: SYNAGEVA

Corticoides para la prevención de las complicaciones de la vía aérea pos-extubación en niños críticos.

• Código: FIBHGM-ECNC003-2010 (FIBHGM-10-01)
• Promotor: Fundación Para la Investigación Biomédica del Hospital Gregorio Marañón

Estudio multicéntrico aleatorizado, doble ciego, comparando el uso de la hipotermia corporal total moderada precoz con topiramato o placebo en recién nacidos asfixiados evolucionando a encefalopatía hipóxico-isquémica moderada-severa.

• Entidad promotora: Instituto de Investigación La Fe
• Estudio HYPOTOP.
• Nº EudraCT:2011-005696-17.
• Duración: 2012-2017

Estudio Synageva LAL-CL02 A Multicenter, Randomized, Placebo-Controlled Study of SBC-102 in Patients with Lysosomal Acid Lipase Deficiency

• Entidad promotora: SYNAGEVA.
• Año de realización: 2015-2017

• Charlas Día Nacional de la Nutrición (28/5/2019)