Group LeaderLocation and ContactMembersLines of ResearchNotable PublicationsProjectsPhD ThesesPatents and TrademarksNews
Eliecer Coto García
Genética Molecular – Laboratorio medicina
Hospital Universitario Central de Asturias (HUCA)
Av. Hospital Universitario, s/n, 33011 Oviedo, Spain.
Telephone: +34 985105500 EXT 37481
E-mail: eliecer.coto@sespa.es
| Name | Organisation | Activity | Euraxess classification |
|---|---|---|---|
| Coto García, Eliecer | SESPA/Universidad de Oviedo | Research/Clinical/Teaching | R4 |
| Cuesta Llavona, Elías | FINBA | Research | R1 |
| Gómez de Oña, Juan | SESPA | Research/Clinical | R3 |
| Rodríguez Reguero, Jose Julián | SESPA | Research/Clinical | R2 |
| Tranche Iparaguirre, Salvador | SESPA | Research/Clinical/Teaching | R2 |
| Velázquez Cuervo, Lucinda | FINBA | Research | R1 |
| Viejo Díaz, Mónica | SESPA | Research/Clinical | R2 |
| Alonso González, María Belén | FINBA | Research | No classification |
| García Lago, Claudia | FINBA | Research | No classification |
| Iglesias Álvarez, Sara | FINBA | Research | No classification |
History of the Group
The group was formed because of a shared interest in the line of research, which focuses on care work in the field of cardiovascular and renal genomics.
Current and future priorities: to delineate the genetic bases of cardiovascular disease and kidney disease.
- Genetics of cardiovascular disease and kidney disease
- Immunogenetics
- MicroRNAs
- Cardiovascular epigenetics
- Genetic association studies
- Genetic epidemiology
- AUTHORS: Gómez J, Lorca R, Reguero JR, Morís C, Martín M, Tranche S, Alonso B, Iglesias S, Alvarez V, Díaz-Molina B, Avanzas P, Coto E.
TITLE: Screening of the Filamin C Gene in a Large Cohort of Hypertrophic Cardiomyopathy Patients.
JOURNAL: Circ Cardiovasc Genet. Apr;10(2). pii: e001584.
YEAR: 2017
ISSN: PMID: 28356264
IMPACT FACTOR: 3.808
QUARTILE AND FIELD: Q1 – Cardiovascular - AUTHORS: Riobello C, Gómez J, Gil-Peña H, Tranche S, Reguero JR, de la Hera JM, Delgado E, Calvo D, Morís C, Santos F, Coto-Segura P, Iglesias S, Alonso B, Alvarez V, Coto E.
TITLE: KCNQ1 gene variants in the risk for type 2 diabetes and impaired renal function in the Spanish Renastur cohort.
JOURNAL: Mol Cell Endocrinol. Mar 9. pii: S0303-7207(16)30055-7.
YEAR: 2016
ISSN: PMID: 26970180
IMPACT FACTOR: 4.405
QUARTILE AND FIELD: Q1 – Endocrinology - AUTHORS: Coto-Segura P, González-Fernández D, Batalla A, Gómez J, González-Lara L, Queiro R, Alonso B, Iglesias S, Coto E.
TITLE: Common and rare CARD14 gene variants affect the anti-TNF response among Psoriasis patients.
JOURNAL: BRITISH J DERMATOLOGY 2016 Jul;175(1):134-41.
YEAR: 2016
ISSN: PMID: 26854129
IMPACT FACTOR: 4.275
QUARTILE AND FIELD: 1st DECILE – DERMATOLOGY - AUTHORS: Batalla A, Coto E, González-Fernández D, González-Lara L, Gómez J, Santos-Juanes J, Queiro R, Coto-Segura P.
TITLE: The Cw6 and late-cornified envelope genotype plays a significant role in anti-tumor necrosis factor response among psoriatic patients.
JOURNAL: Pharmacogenet Genomics. 2015 Jun; 25(6):313-316.
YEAR: 2015
ISSN: PMID: 25794162
IMPACT FACTOR: 3.481
QUARTILE AND FIELD: Q1 – GENETICS - AUTHORS: Batalla A, Coto E, González-Lara L, González-Fernández D, Gómez J, Aranguren TF, Queiro R, Santos-Juanes J, López-Larrea C, Coto-Segura P.
TITLE: Association between single nucleotide polymorphisms IL17RA rs4819554 and IL17E rs79877597 and Psoriasis in a Spanish cohort.
JOURNAL: J Dermatol Sci. 2015 Nov; 80(2): 111-5.
YEAR: 2015
ISSN: PMID: 26347322
IMPACT FACTOR: 3.739
QUARTILE AND FIELD: Q1-DERMATOLOGY - AUTHORS: Tavira B, Gómez J, Diaz-Corte C, Suarez B, Coronel D, Arias M, López-Larrea C, Iglesias S, Alonso B, Rodrigo E, Coto E.
TITLE: ABCB1 (MDR-1) pharmacogenetics of tacrolimus in renal transplanted patients: a Next Generation Sequencing approach.
JOURNAL: Clin Chem Lab Med. 2015 Sep 1; 53(10): 1515-9.
YEAR: 2015
ISSN: PMID: 25781547
IMPACT FACTOR: 3.017
QUARTILE AND FIELD: Q1-LABORATORY MED. - AUTHORS: Gómez J, Gil-Peña H, Santos F, Coto E, Arango A, Hernandez O, Rodríguez J, Nadal I, Cantos V, Chocrón S, Vergara I, Madrid Á, Vazquez C, González LE, Blanco F.
TITLE: Primary distal renal tubular acidosis: novel findings in patients studied by next-generation sequencing.
JOURNAL: Pediatr Res. 2016 Mar; 79(3): 496-501.
YEAR: 2016
ISSN: PMID: 26571219
IMPACT FACTOR: 2.761
QUARTILE AND FIELD: Q1- PAEDIATRICS - AUTHORS: Gómez J, Reguero JR, Coto E.
TITLE: The Ups and Downs of Genetic Diagnosis of Hypertrophic Cardiomyopathy.
JOURNAL: Rev Esp Cardiol (Engl Ed). 2016 Jan; 69(1): 61-8.
YEAR: 2016
ISSN: PMID: 26654849
IMPACT FACTOR: 4.596
QUARTILE AND FIELD: Q1-CARDIOLOGY - AUTHORS: Pablo Flórez J, García D, Valverde I, Rubín J, Pérez D, González-Vasserot M, Reguero J, María de la Hera J, Avanzas P, Gómez J, Coto E, Morís C, Calvo D.
TITLE: Role of syncope in predicting adverse outcomes in patients with suspected Brugada syndrome undergoing standardized flecainide testing.
JOURNAL: Europace. 2018 Jun 1; 20(FI1): f64-f71.
YEAR: 2018
ISSN: PMID: 29309564
IMPACT FACTOR: 4.021
QUARTILE AND FIELD: Q2-CARDIOLOGY - AUTHORS: Lorca R, Gómez J, Martín M, Cabanillas R, Calvo J, León V, Pascual I, Morís C, Coto E, R Reguero JJ.
TITLE: Insights Into Hypertrophic Cardiomyopathy Evaluation Through Follow-up of a Founder Pathogenic Variant.
JOURNAL: Rev Esp Cardiol (Engl Ed). 2018 Apr 6. pii: S1885-5857(18)30053-7.
YEAR: 2018
ISSN: PMID: 29631964
IMPACT FACTOR: 4.596
QUARTILE AND FIELD: Q1-CARDIOLOGY / CARDIOVASCULAR - AUTHORS: Coto E, Calvo D, Reguero JR, Morís C, Rubín JM, Díaz-Corte C, Gil-Peña H, Alosno B, Iglesias S, Gómez J.
TITLE: Differential methylation of lncRNA KCNQ1OT1 promoter polymorphism was associated with symptomatic cardiac long QT.
JOURNAL: Epigenomics. 2017 Aug; 9(8): 1049-1057.
YEAR: 2017
ISSN: PMID: 28749187
IMPACT FACTOR: 4.044
QUARTILE AND FIELD: Q1-GENETICS - AUTHORS: Batalla A, Coto E, Gómez J, Eirís N, González-Fernández D, Gómez-De Castro C, Daudén E, Llamas-Velasco M, Prieto-Perez R, Abad-Santos F, Carretero G, García FS, Godoy YB, Cardo LF, Alonso B, Iglesias S, Coto-Segura P.
TITLE: IL17RA gene variants and anti-TNF response among psoriasis patients.
JOURNAL: EPharmacogenomics J. 2018 Jan; 18(1): 76-80.
YEAR: 2018
ISSN: PMID: 27670766
IMPACT FACTOR: 3.784
QUARTILE AND FIELD: Q1-GENETICS - AUTHORS: Calvo D, Rubín JM, Pérez D, Gómez J, Flórez JP, Avanzas P, García-Ruíz JM, de la Hera JM, Reguero J, Coto E, Morís C.
TITLE: IL17RA gene variants and anti-TNF response among psoriasis patients.
JOURNAL: Heart Rhythm. 2015 Feb; 12(2): 350-7.
YEAR: 2015
ISSN: PMID: 25460174
IMPACT FACTOR: 4.391
QUARTILE AND FIELD: Q1-CARDIOVASCULAR - AUTHORS: Batalla A, Coto E, González-Lara L, González-Fernández D, Gómez J, Aranguren TF, Queiro R, Santos-Juanes J, López-Larrea C, Coto-Segura P.
TITLE: Association between single nucleotide polymorphisms IL17RA rs4819554 and IL17E rs79877597 and Psoriasis in a Spanish cohort.
JOURNAL: J Dermatol Sci. 2015 Nov; 80(2): 111-5.
YEAR: 2015
ISSN: PMID: 26347322
IMPACT FACTOR: 3.739
QUARTILE AND FIELD: Q1-DERMATOLOGY
| Principal Investigator | Title | Funding Body | Reference No | Duration | Amount | Researchers |
|---|---|---|---|---|---|---|
| Eliecer Coto García | Hypertrophic cardiomyopathy: identification of new genes through exome sequencing. | Instituto Salud Carlos III | PI 12/00287 | January 2013 – December 2015 | €75,000 | Eliecer Coto García Julián R. Reguero Juan Gómez de Oña |
| Eliecer Coto García | Hypertrophic cardiomyopathy: mutation spectrum and functional characterisation of new genes identified through exome sequencing. | Instituto Salud Carlos III | PI15/00342 | January 2016 – December 2018 | €104,665 | Eliecer Coto García Julián R. Reguero Juan Gómez de Oña |
| Juan Gómez de Oña | Long noncoding RNAs in hypertrophic cardiomyopathy: the role of genetic variation in risk and as a modifier of phenotype. | Instituto Salud Carlos III | PI17/00648 | January 2018 – December 2020 | €95,000 | Julián R. Reguero Juan Gómez de Oña |
| Eliecer Coto García | REDINREN (Renal Research Network) | Instituto Salud Carlos III | RD-16/009/005 | January 2018 – December 2020 | €75,000 | Eliecer Coto García Julián R. Reguero Juan Gómez de Oña |
| Supervisors | Title | PhD Student | Organisation | Date of Viva | International Honours |
|---|---|---|---|---|---|
| Eliecer Coto García Julián Rodríguez Reguero |
Identification of new genes in hypertrophic cardiomyopathy through exome sequencing | Juan Gómez de Oña | Universidad de Oviedo | February 2017 | No |
| Eliecer Coto García Julián Rodríguez Reguero |
Correlation between genotype and phenotype in non-compaction cardiomyopathy | Rebeca Lorca García | Universidad de Oviedo | January 2018 | No |
| Eliecer Coto García Pablo Coto Segura |
IL17 pathway genes in psoriasis and response to biological treatments | Ana Batalla Cebey | Universidad de Oviedo | February 2016 | No |
| Eliecer Coto García Pablo Coto Segura |
Genetics of the TNF/NFKB pathway in psoriasis and response to biological treatments | Leire González Lara | Universidad de Oviedo | September 2018 | No |
| Eliecer Coto García Pablo Coto Segura |
The pharmacogenetics of anti-TNFs in psoriasis | Noemí Eirís Salvado | Universidad de Oviedo | June 2017 | No |
